All those Mac weirdos out there will be happy to learn that Michael Mancuso has created a OS X program to edit Doom lumps entitled Wad Builder, which according to the author
has two basic functions. It can decompile a wad file into a folder with a file for each lump and a file to keep track of the lump order, and it can take one of these folders and turn it into a functional wad again. While it doesn't have support for editing graphics and sounds, it's a basic solution that should allow you to put DeHackEd patches and FraggleScripts into your wads.
Also he sent along word of a new update to the Mac level editor Hellmaker Enhanced, which now has Fragglescript support.