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Although it's possible, there doesn't have to be any particular "cause" or reason why something like this would develop. As geekmarine says, for example, paranoid schizophrenia often develops in the early 20s. It's probably a waste of time trying to find a "cause" for it because there likely isn't one.
That said, smoking weed really isn't likely to help things.
Regarding another brilliant person and his schizophrenia.