For regular play, no, not at all.
I've been playing DOOM with source-ports more or less since their inception, and as they've gradually evolved, allowing for hi-res display modes, and other bells and whistles, the experience has become, by quite small increments, increasingly removed from my experience of playing vanilla DOOM in '94, to the point where (for me) the two are fundamentally unalike. This is not a complaint; it's just that, as such, my day-to-day experience of playing new maps (or at least, maps that I didn't play back then) via source ports, lacks any element of nostalgia.
But occasionally I want a nostalgia trip, and - if so - I play vanilla via DOS-box, but only the IWAD maps, or maps from that period. It has to be DOS-box, rather than choco-DOOM, because I want to see that "THIS IS NOT SHAREWARE" loading screen. I don't do this very often though (maybe once a year) lest, with regular contact, it lose its nostalgic edge. This is actually a nice thing about the early emergence of source ports, since if I'd been regularly playing vanilla DOOM for the past 20 years, I doubt it would feel very nostalgic to play it now.