The stories I could tell! A few months ago, I got a BSOD. When I restarted, everything was alright for a bit, until I restarted Firefox. All my bookmarks had gone; downloads refused to work. I kept getting NSIS errors, and if I tried to move or delete anything it said the directories were "corrupted and unreadable"! I ended up having to run things off my mother's old laptop for a bit until I was advised to run Chkdsk and let the machine handle it. That solved my little problem. But after that I tried to cut down on having to use the reset button on my rig.
Recently, my CD-ROM drive just stopped. It gave me an Error 19. Restarting didn't help, so I had to delete some things in the registry and reinstall the drivers. It worked afterwards.
Then there was the time I completely forgot my password to my user account.